Friday, August 29, 2014

End is in sight

"Doing a dissertation marks the transition from a student to a scholar."

I picked an interesting topic.

Discuss the public health implications of the spread of New Delhi Metallo-beta lactamase (NDM-1) among gram negative bacteria.

I have always liked microbiology.

NDM-1 is something produced by a bacteria that rendera antibiotics useless. It is scary because those antibiotics are powerful ones, usually used when all other antibiotics failed. These antibiotic are known as Carbapenem such as imipenem to name one.

With its ability to deactivate the most powerful antibiotics, it gets worse when we talk about its spreading capabilities.The gene encoding for NDM-1 is encoded on plasmids that can be easily passed from one type of bacteria to another. Within the plasmid, the gene NDM-1 exist near integrons which I don't know yet. Some big deal with it being within the class 1 integrons and being above to species hop when compared to other resistance enzyme such as VIM.

This gene is spreading here and there and everywhere.

If it becomes common, part of the normal flora than we really cannot afford to be infected. Blablablablabla.

Getting nowhere.

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